|
KMID : 1155520150100040267
|
|
Anesthesia and Pain Medicine
2015 Volume.10 No. 4 p.267 ~ p.270
|
|
|
A case of postoperative serotonin syndrome following the administration of fentanyl, palonosetron, and meperidine -A case report-
|
|
Lee Chiu
Kim Eun-Ju
Joe Soo-Hyun
Ban Jong-Seouk
Lee Ji-Hyang
An Ji-Hyun
|
|
|
Abstract
|
|
|
|
Serotonin syndrome is an unexpected adverse reaction of serotonergic medication. Some drugs used by anesthesiologists may cause serotonin syndrome. Serotonin syndrome is known to be related to 5-hydroxytryptamine 1A and 5-hydroxytryptamine 2A agonism. However, recent research has revealed evidence that 5-hydroxytryptamine 3 (5-HT3) antagonism can also play a role in serotonin syndrome. Among the 5-HT3 antagonists, palonosetron is the most highly specific. In this study, we present the first case of fentanyl- and meperidine-induced serotonin syndrome precipitated by palonosetron in general anesthesia.
|
|
|
KEYWORD
|
|
|
Fentanyl, Meperidine, Palonosetron, Serotonin, Serotonin syndrome
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|